“All things are created twice; first mentally; thenphysically.”-Stephen Covey, 7 Habits of Highly Effective People The genesis of actionis the role of the upper motor neuron which happens in the motor cortex of thecerebrum. In the spinal cord, the upper motor neuron structurally traverses torendezvous with the lower motor neuron which physically conveys theinstructions to the skeletal muscle. In a nutshell, the upper motor neuronsbrainstorms, while the lower motor neuron performs. 2. Astrocytesare multi-taskers as they perform diverse roles from logistical support thruthe shipment of nutrients, juggling the correct ion concentration andreconstruction during neuronal damage. Due to the core function of astrocytewith repair and maintenance, reactive astrongliosis as response to injury andinfection is a hallmark feature of CNS disturbance.
Microglia is the “Cookie Monster” of the central nervoussystem which gobbles up plaques, injured neurons, synapses and pathogens in the central nervous system.The microglial antipodal extremes of low activity (Autism) to over activity (Alzheimer’s) pathological effects. Too many connections of neurons can overwhelm thesenses and explains the hyperactivity of autistic individuals.
Oligodendrocytes produces myelinsheath to coveraxons as insulation in the central nervous system. Lack of myelination occurswhen oligodendrocytes die, and unmyelinated neurons cannot function properly asseen in multiple sclerosis.