Orphenadrine hydrochloride is used to treat Parkinsonism. It isimportant to differentiate between Parkinson’s Disease and Parkinsonism.Parkinsonism is a blanket term that encapsulates a variety of neurological syndromesthat can manifest themselves with symptoms similar to Parkinson’s Disease, namelyslow movement (bradykinesia) tremor, rigidity, and postural instability. Thereare a variety of disorders that fall into this category, and since the symptomsare similar to those that present in a patient with Parkinson’s disease, it is hardto diagnose the individual on the basis of this similarity. Parkinson’sDisease, on the other hand is a degenerative CNS disorder that affectsmovement, and is normally irreversible, with treatment focusing on reducing symptoms.On the other hand, treatment of conditions that result in Parkinsonism with adrug such as orphenadrine hydrochloride may improve or result in thealleviation of symptoms