Beneficial effects of the parasite on Autismpatients:After studying the hygiene hypothesiswhile researching confusing links between autism and immunity, the father of anautistic patient, Stewart Johnson came with the idea of treating Autism patientwith parasitic worms (ncbi, 2010).Stewart treated his teenage son with eggsfrom the helminth Trichuris suis under Dr. Hollander’ssupervision, Trichuris suis infects and is harmful to pigsbut it is not pathogenic in humans. With continued treatment, purposelessbehaviours, resistance to change, and irritability all decreased in Stewart’sson, said Hollander (Sabrina Richards, 2012).
Although no defined standard approachexists , currently ASD treatments can be divide into nutritional, medical and behaviouralapproaches (Siniscalco& Antonucci, 2013a). To treat behavioral problems, such asanger, impaired verbal, self-injurious behaviour, that keep the person with anautism from functioning more efficiently in community, medications are oftenused (NationalInstitute of Mental Health, 2016). Nowadays helminthic therapy showspotential and can be use as anti-inflammatory agents, it used by the inoculation of the patient with specific parasiticintestinal nematodes (helminths). There is many studies on anumber of such organisms are currently being investigated for their use astreatment including Trichuris suis ova (ovamed, 2013) ,(Fleminget al., 2011).
commonlyknown as pig whipworm eggs, Necator americanus ( Nottingham, 2017) commonly known as hookworms; Trichuris trichiura ova commonly referred to as humanwhipworm eggs . Several human diseases can be treated with helminths. Trichurissuis ova show strong immunomodulatory properties.
TSO could be a moderntherapeutic option for ASD treatment. Some studies hypothesize that TSO couldbe useful in addressing ASD immune dysregulations. (Siniscalco& Antonucci, 2013b). The harmful effect of the parasite on autismpatient:Although data suggesting increasedsusceptibility to helminth infection in pregnant women are incompatible, helminthinfections, in general, affect both mother and fetus, data have shown thatsevere anemia, malnutrition, and recurrent infectious processes increase therisk for maternal and infant morbidity and mortality (Woodburnet al.
, 2009)(Friedman,Mital, Kanzaria, Olds, & Kurtis, 2007).Anemia in these highlyendemic regions is common among pregnant women. Anemia in these pregnancy hasbeen associated with stillbirth, prematurity, and low birth weight (Larocque, Casapia, Gotuzzo, & Gyorkos, 2005)(Elliott et al., 2011). Helminth infections have been shown to directlycontribute to severe anemia in patients through blood loss and micronutrientdeficiencies some of these helminth infections include hookworm, trichuriasis,and schistosomiasis (Mpairwe, Tweyongyere, & Elliott, 2014)( Steketee RW, 2003) Hookworm is theleading cause of pathologic blood loss in endemic areas.In Western society, Study of diseasescaused by helminths show that they have recently discovered that some childrenwith autism are infected with a large number of intestinal worms, calledhelminths (Parker, W. and J.
Ollerton, 2013). Parents detect that removal ofsome of these helminths can improve some of the symptoms of autism in somecases, at least temporarily (Raison, C.L., C.A. Lowry, and G.
W. Rook, 2010).This has led some parents to conclude that helminths are a causative agent inthe pathogenesis of autism and that strict measures should be taken to removethem (Parker, W.
and J. Ollerton, 2013)( Raison, C.L., C.
A. Lowry, and G.W.Rook, 2010).