Green protocol for the synthesis of 1, 8-dioxodecahydroacridines using citric acid as organocatalyst Monika Patil1, Shrikrishna Karhale1, Ananda Kudale 1 Arjun Kumbhar2, Sagar More2, Vasant Helavi*1 1Department of Chemistry, Rajaram College, Kolhapur 416004, Maharashtra, India. 2Department of Chemistry, P. D. V. P. College, Tasgaon 416312, Maharashtra, India. E-mail: [email protected] *Corresponding author: Tel.: +91 231 2537840; …

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Cells have developed different monitoring mechanisms to target messenger RNA (mRNA) with mutations that otherwise would cause errors in protein synthesis and furthermore eradicate other incorrectly processed cellular RNAs. These processes function in both cell nucleus and cytoplasm. One of the best-observed RNA monitoring pathways is the Nonsense-Mediated mRNA Decay (NMD) pathway. (Mechanism and regulation…). …

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