Now-a-days people are suffering from skin diseases. If skindiseases are not treated at earlier stage, then it may lead to complications inthe body including spreading of the infection from one individual to the other.
The skin diseases can be prevented by investigating the infected region at anearly stage. The characteristic of the skin images are diversified, so that itis challenging job to devise an efficient and robust algorithm for automaticdetection of the skin disease and its severity. Skin tone and skin color playan important role in skin disease detection.
Color and coarseness of skin arevisually different. Here we consider two diseases – Granular parakeratosis and Pemphigus.Granular parakeratosis is a rare and benign skin disease thatpresents as erythematous to brown hyperkeratotic papules that can coalesce intoplaques. The term “granular parakeratosis” is used to describe notonly the skin condition, but also a distinctive histological reactive patternon biopsy specimens that are either regarded as the disease itself, or as anincidental finding. Granularparakeratosis (GP) consists of the presence of brown or redish hyperkeratoticpapullae and plaques, with size ranging from one to four milimeters, located inintertriginous areas. Most reports describe GP in persons over 40 years of age.However, all age groups may be affected, including children 1. There is onereport of congenital GP.
It has been first described in the axillary folds ofadults, but later observed in other cutaneous folds, such as sub andintermammary, abdominal, inguinal and perianal ones. Later on, GP was alsoobserved in children with lesions in the perianal area and folds. GP is found more often in women than in men. In women, lesions occur in submammary region, axillaeand popliteal fossa; in men, groin and genital region.
Clinically two different patterns are recognized: lichenplanus-like red-brown slightly hyperkeratotic or scaly papules, and largerplaques which are either bright red shiny or grey-brown with lichenification. Themost striking feature marked is thickening of the stratum corneum, which ishypereosinophilic. Keratohyaline granules and keratinocyte nuclei were retainedthroughout the thickness of the stratum corneum, and appeared somewhat roundedand irregular in shape compared to the granular layer. The disease caused a burning sensation in the area of granularparakeratosis.
The patient is overweight or haschronic moisture in the intertriginous areas. GPhas been associated with dermatomyositis, molluscum contagiosum, and cancer.